Symposium Overview and Purpose

The Emerging Pathways With Therapeutic Potential in Cancer symposium will focus on emerging targets in cellular pathways, such as proliferation and growth, angiogenesis, and apoptosis in cancer therapy. Further, means to harness the host immune system will also be discussed. This multidisciplinary meeting will provide in-depth coverage of cutting-edge translational cancer research, highlighting the most promising novel therapeutics. The symposium will describe the mechanisms of action of novel agents that are currently in clinical development as well as the potential impact of these targeted agents on treatment outcome over the next 5-10 years. The program will consist of a mixture of didactic lectures and moderated discussions. Leading oncology experts will participate as faculty.

This presentation was selected by the American Society of Clinical Oncology® as an independent educational activity held in conjunction with an ASCO® meeting. This presentation is not sponsored or endorsed by ASCO.

Target Audience

This educational program is directed toward medical oncologists interested in reviewing the most recent clinical trial data on therapeutic treatments in cancer. Surgical and radiation oncologists and other health professionals interested in the treatment of cancer are also invited to attend.

CME Accreditation and Credit Designation

Physicians’ Education Resource is accredited by the Accreditation Council for Continuing
Medical Education to provide continuing medical education for physicians.

Physicians’ Education Resource designates this educational activity for a maximum of 2 AMA
PRA Category 1 Credits™
. Physicians should only claim credit commensurate with the extent
of their participation in the activity.

Learning Objectives

At the conclusion of this symposium, you should be able to:

    • Outline the key signaling pathways and cellular processes involved in tumorigenesis
    • Describe the rationale for targeting the ERK/MEK pathway in cancer
    • Assess the role of the PI3K/Akt signaling pathway in oncogenesis
    • Review the rationale for targeting the insulin-like growth factor (IGF) pathway in cancer
    • Examine the role of angiogenesis in tumor growth and metastasis
    • Assess the efficacy and safety of novel agents that target ERK/MEK, PI3K/Akt, IGF/IGF-1
      receptor, and angiogenic proteins
    • Discuss the selection of MAGE3 as a target and review clinical vaccine development in
      lung cancer and melanoma

Acknowledgement

This activity is supported by an educational grant from: